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The set consists of heavy armor and jewelry in all slots, as well as weapons and shields of all types. Unique pieces include:
- Dres Dirk, a quest reward for Mechanical Murder
- Redoran General's Gauntlets
- Gruznak's Chestplate
- Dungeon-Delving Slippers, a quest reward for The Light Fantastic
- Plague Doctor Celdien's Pauldrons
- Plague Doctor Llarel's Sheltering Shield
- Plague Doctor's Talisman of Bthanual
- Plague Doctor's Dremora's Dread
Zones drop pieces from their sets:
- Delve bosses drop a waist, foot, or unique item piece.
- Overland bosses drop a head, chest, leg, weapon, or unique item piece.
- Public dungeon bosses drop a shoulder, hand, weapon, or unique item piece.
- Chests at Dark Anchors drop a jewelry set piece.
- Treasure chests chance to grant any set piece that can drop in that zone, increased by having the Treasure Hunter champion perk.
- Many quest rewards are part of overland sets.