Totambu borders Lainlyn to the northwest, Satakalaam to the north, Mournoth to the northeast, the Dragontail Mountains to the south, and Kozanset to the west. The main deity of this Redguard-dominated region was Zenithar. The military force of Totambu was the Order of the Scarab. They also served as the official guard for the royal family of Totambu dwelling in the city of Totambu. The Khulari clan was the predominant vampire bloodline in the region.
After the Warp in the West, Totambu came under the dominion of the Kingdom of Sentinel ruled by the Forebears faction. Later, however, it became a site of a Crown rebellion against King Lhotun of Sentinel. Totambu declared independence from Sentinel and pledged allegiance to the Crown leader Ayaan-si, High Prophet of Elinhir. Even though Lhotun's kingdom surrounded Totambu on all four sides, its people kept holding their resistance.
- The city of Na-Totambu in the Alik'r was named after the old Yokudan capital on the island of Akos Kasaz.