Lyrezi is one of the vampire bloodlines of the Iliac Bay area. Those of the bloodline are gifted with the ability to turn invisible and magically silence their enemies. The bloodline dominates an area of High Rock - specifically the regions of Alcaire, Koegria, Menevia, Orsinium Area, the Wrothgarian Mountains and Balfiera. They are the enemies of the Garlythi bloodline.
The bloodline is named after Lyrezi, a tribal Nede from ancient Skyrim who was involved in the attempted cremation of Lamae Bal, the first vampire. After awakening on the pyre, Lamae brutally raped the men of the tribe, seemingly passing on the gift of vampirism in the process.
For game-specific information, see the Daggerfall article.