Skyrim:Journal (Harmugstahl)

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Book Information
ID 0008E5DF
Value 5 Weight 1
Found in the following locations:
About experiments for infusing elemental energy into Frostbite Spiders

Notes and Results
It would seem the smaller specimens cannot survive the infusion process. Application of the serum results in a short burst of elemental energy, followed by death. I will have to change the formula before trying again.
The larger subjects, however, have taken to the transformation nicely. For now, they are stored away in their pens until I can examine them further.