Many Non-Player Characters, or NPCs, may be found in Redguard. Unlike previous Elder Scrolls games, all of them have voiced dialogue. Most are unique, but there are a few classes of generic NPCs, such as guards and island thugs. It's not possible to attack unarmed people; Cyrus will simply comment, "No, s/he's unarmed."
Conversing with the inhabitants of Stros M'Kai is central to advancing the storyline. Talking to one person may open up new dialogue options with others. Each NPC's article includes their complete dialogue and how to unlock the various topics of discussion.
Four classes of generic NPCs exist in the game. The pirates wandering around town are always friendly and the island thugs wandering outside are always hostile. Guards will only attack you if your weapon is drawn, you have attacked them, or after the quest Escape the Catacombs. Tavern thugs are found in the Draggin Tale Inn and can start a brawl with Cyrus. Similar to goblins, guards have elite variants with more health.